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Publication
  • ACR •
  • 29 October, 2025 •
  • •

PAXIS: A Randomized, Double-Blind, Placebo-Controlled, Dose Finding Phase 2 Study (Part 1) Followed by an Open-Label Period (Part 2) to Assess the Efficacy and Safety of Pacritinib in Patients with VEXAS Syndrome

David B. Beck, Mael Heiblig, Sinisa Savic, Marcela A. Ferrada, Arsene Mekinian, Onima Chowdhury, Danielle Hammond, Lachelle D. Weeks, Carmelo Gurnari, Yohei Kirino , Sophie Georgin-Lavialle, Sarah A. Buckley, Bryan G. Harder, Sandra Goble, Matthew J. Koster

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Oral Presentation
Publication
  • ACR •
  • 28 October, 2025 •
  • •

Characterization of Infusion Reactions Within 1 Hour of Treatment With Nanoencapsulated Sirolimus Plus Pegadricase: Pooled Results From the Phase 3 DISSOLVE I and DISSOLVE II Trials

Herbert Baraf, Andrew Sulich, Guillermo Valenzuela, Rehan Azeem, Ben Peace, Bhavisha Desai, Herbert Baraf

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Poster
Publication
  • ACR •
  • 28 October, 2025 •
  • •

Economic Burden of Macrophage Activation Syndrome (MAS) in Patients with Still’s Disease (Systemic Juvenile Idiopathic Arthritis (sJIA) and Adult-onset Still’s Disease (AOSD): Analysis of a US National Administrative Claims Database

Michael Marrone, Christopher McPherson, Abiola Oladapo

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Poster
Publication
  • ACR •
  • 28 October, 2025 •
  • •

Nanoencapsulated Sirolimus Plus Pegadricase Reduced Disease Burden in Patients With Uncontrolled Gout: Results From the Phase 3 DISSOLVE Trials

Puja Khanna, Amar Majjhoo, Rehan Azeem, Ben Peace, Bhavisha Desai, Vibeke Strand

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Oral Presentation
Publication
  • EULAR •
  • 14 June, 2025 •
  • •

PAXIS: A Randomized, Double-Blind, Placebo-Controlled, Dose Finding Phase 2 Study (Part 1) Followed by an Open-Label Period (Part 2) to Assess the Efficacy and Safety of Pacritinib in Patients with VEXAS Syndrome

David B. Beck, Mael Heiblig, Sinisa Savic, Marcela A. Ferrada, Arsene Mekinian, Onima Chowdhury, Danielle Hammond, Lachelle D. Weeks, Carmelo Gurnari, Yohei Kirino , Sophie Georgin-Lavialle, Sarah A. Buckley, Bryan G. Harder, Sandra Goble, Matthew J. Koster

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Poster
Publication
  • EULAR •
  • 14 June, 2025 •
  • •

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS-DAI)

Kevin Byram, Herman Mann, Danielle Hammond, Sinisa Savic, Yohei Kirino , Carmelo Gurnari, Mael Heiblig, Thibault Comont, Arsene Mekinian, Mrinal Patnaik, Lachelle D. Weeks, Gary Ho, Onima Chowdhury, Adam Al-Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin-Lavialle, Peter Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Sandra Goble, Matthew J. Koster, David B. Beck

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Poster
Publication
  • EULAR •
  • 13 June, 2025 •
  • •

Development of a Consensus Definition of VEXAS Flare for Use in Clinical Research

Lachelle D. Weeks, Danielle Hammond, Sinisa Savic, Mael Heiblig, Onima Chowdhury, Arsene Mekinian, Carmelo Gurnari, Radhakrishnan Ramchandren, Sophie Georgin-Lavialle, Marcela A. Ferrada, Sarah A. Buckley, Bryan G. Harder, Sandra Goble, David B. Beck, Matthew J. Koster

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Poster
Symposium
  • EULAR •
  • 13 June, 2025 •
  • •

Putting on your VEXAS goggles: Seeing what’s in plain sight​

Sophie Georgin-Lavialle, Thibault Mahevas, Lachelle D. Weeks, Sara Bindoli

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Slides Video
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