Publication
  • ESPN •
  • 2 October, 2026 •
  • •

Pegcetacoplan treatment response in VALIANT/VALE: Impact of genetic and acquired complement dysregulation and disease type in C3 glomerulopathy and primary (idiopathic) immune complex membranoproliferative glomerulonephritis

Nicole Van De Kar, Marina Norris, Daniel P Gale, Sophie Chauvet, Fernando Caravaca-Fontán, Julia Weinmann-Menke, Bradley P Dixon, Carla M Nester, Lucía Quintana-Gallardo, Johan Szamosi, Kathryn Gordon, Anwesha Mukherjee, Fadi Fakhouri

Publication
  • ESPN •
  • 2 October, 2026 •
  • •

Real-world effectiveness and safety of pegcetacoplan in patients with C3 glomerulopathy or primary immune-complex membranoproliferative glomerulonephritis: PRISM-C3, a multi-country Phase 4 study

David Kavanagh, Matthew C Pickering, Terence Cook, Marina Vivarelli, Moglie Le Quintrec, Véronique Frémeaux-Bacchi, Virginia Taliadouros, Elena Surova, Nicholas Webb, Fadi Fakhouri

Publication
  • ERA •
  • 4 June, 2026 •
  • •

Safety and low incidence of meningococcal infections with pegcetacoplan in C3G / primary IC-MPGN and PNH

Antonio Mastrangelo, Daniel P Gale, Daniel Zecher, Nabil Melhem, Sanya Norouzi, Bradley P Dixon, Sheena Patel, Liza Alkhori Franzén, Gashu Ayehu, Chauncey Clemons, Régis Peffault de Latour

Available materials

Oral Presentation
Publication
  • ERA •
  • 4 June, 2026 •
  • •

Epidemiology of C3G and primary IC-MPGN: a systematic literature review and meta-analysis

Fernando Caravaca-Fontán, Carly Rich, Veruska Carboni, Jameel Nazir, Chris D Poole, Daniel P Gale

Available materials

Poster
Publication
  • ERA •
  • 4 June, 2026 •
  • •

Pegcetacoplan population pharmacokinetics and exposure-response analysis in adolescent and adult patients with C3G or primary IC-MPGN

David Kavanagh, Seung Hyeok Han, Larry A Greenbaum, Bradley P Dixon, Ali Keshavarz, Ryan L Crass, Brandon Smith, Xiaoying Yu, Priska Kaufmann

Available materials

Poster
Publication
  • ERA •
  • 4 June, 2026 •
  • •

Pegcetacoplan sustained clinical benefit in C3G and primary IC-MPGN through 1 year of therapy: Data from VALIANT/VALE

Fadi Fakhouri, Gema Ariceta, Matthew C Pickering, Moglie Le Quintrec, Marina Vivarelli, Carla M Nester, Bradley P Dixon, Virginia Taliadouros, Johan Szamosi, Kathryn Gordon, Anwesha Mukherjee, Christoph Licht

Available materials

Oral Presentation
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